Thursday, 6 September 2018

Now Treat Cartilage Degeneration With Your Own Blood Platelets

Platelet-rich plasma therapy (PRP) attempts to take advantage of the blood's natural healing properties and help in the revival of cartilage to improve function and thereby reducing pain.  The arrival of orthobiologicals like PRP and stem cells are used to achieve great results in case of ruptured muscles, damaged ligaments, and tendons as well as in non- healing fractures. Although the application of PRP has been around for decades, the treatment has become a more holistic kind of option in Osteoarthritis recently as PRP therapy repairs degenerative joints using your own healing growth factors.

People turning to PRP injections to treat an intensifying list of orthopaedic conditions, including osteoarthritis are escalating nowadays. PRP injections have been gaining popularity for a number of applications in orthopaedic surgery as a way to augment both healings of various tissues and decrease pain.  It is most frequently used for knee osteoarthritis, but may be used on other joints as well. The effect of Platelet concentrates on stem cells and chondrocytes has become the major area of focus. The potential for PRP to enhance cartilage regeneration and in the reduction of catabolic factors that lead to cartilage degradation has been well studied recently.


How is PRP therapy done?

  • PRP therapy is like the kickoff in a soccer game. It initiates the curative cascade into the local tissue. Nothing in the body heals without inflammation…absolutely nothing!
  • Your blood platelets play a vital role in blood clotting and injury/wound healing. The preparation and procedure of healing doses of growth factors consisting of a blood from the patient (autologous blood collection) and then placing it in a Centrifuge machine which extracts the Platelet-rich plasma (PRP) constituent from the blood.
  • The sample constitutes of platelets (blood cells) which consist of copious healing and inflammatory chemicals. This PRP sample is injected in the affected area under sterile precautions. This decreases inflammation and promotes healing.
  • In general, patients are treated every 3-6 weeks. Typically three to six visits are essential per region in the body.


Growth and healing factors in PRP?

Few years ago researchers at the University of Florence have established the remedial and repair factors found in platelet concentrates. There are many studies and clinical evidence which support the healing factors in PRP.
  • PDGF (Platelet-derived Growth Factor) initiates connective tissue healing through the promotion of collagen, glycosaminoglycan, and collagenase production by fibroblasts.
  • The most important effect of PDGF seems to be its mitogenesis of mesoderm-derived cells, better extracellular matrix synthesis, and chemotaxis and activation of monocytes, neutrophils, and fibroblasts.
  • Platelet-derived growth factor (PDGF)also plays a major role in inducing phenotypic switching from contractile to proliferative state vascular smooth muscle cells (VSMC’s)
  • The formation of fibrocartilage, cartilaginous and bony calluses is vital for bone healing.
  • The most important specific activity of PDGF is in articular cartilage repair

  • VEGF (Vascular Endothelial Growth Factor) also known as vascular permeability factor (the platelet-derived growth factor family of cystine-knot growth factors) is the chief regulator of angiogenesis and vasculogenesis. This plays an important role in tissue regeneration by generating new pathways of blood vessels for the therapeutic factors to get to the location of the injury.
  • Transforming Growth Factor (TGF) including TGF-b1 stimulates the rate of chondrocyte maturation and decreases the breakdown of cartilage. TGF- beta-mediated signaling pathways and their effects significantly impact the diagnosis and treatment of many common orthopaedic diseases.
The Chennai-based Trauma & Orthopaedic Speciality Hospital (TOSH), an exclusive orthopaedic hospital with international standards has now become one of the renowned Orthopaedic Care Centres in South India. The center offers the entire spectrum of services in trauma and orthopaedics, and also specialize in PRP stem cell therapy in Chennai, trauma surgery and limb reconstruction, PRP treatment for cartilage degeneration and joint restoration, spine surgery, hand surgery, paediatric orthopaedics, arthroscopic surgery, daycare Ortho surgery etc. They are the first ever healthcare unit in the country to launch stem cell and regenerative medicine unit in orthopaedics with a dedicated exclusive operation theatre for stem cell procedures. With world-class facility at affordable cost in all orthopaedic Sub-specialty, the hospital is committed to provide good quality orthopaedic and trauma care to patients from simple fracture treatment to sophisticated joint replacement and arthroscopic procedures.
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Sunday, 26 August 2018

Stemcell Knee Cartilage Regeneration - An Alternate treatment for Knee Arthritis

A revolutionary new approach in the field of medicine has recently come to fruition with the introduction of Stem Cell Knee Cartilage Regeneration technique. In layman’s terms, stem cells isolated and extracted from the bone marrow is then introduced in damaged areas of the body to help the cells to multiply and the body to heal itself.

knee cartilage regeneration chennai

Stem Cell harvest and application is gaining distinctive inroads into all forms of therapeutic procedures, especially in the field of Orthopaedics, for the treatment of Knee Pain. Knee Pain, on account of osteoarthritis, caused due to debilitating effect of age is one of the prime causes of pain and agony to the patients. Conservative treatments initiate with pain relieving medication, physiotherapy, progress to steroid laced injections and ultimately calls for surgical intervention.

However, in most cases the patient does not report significant improvement in pain alleviation and is hence advised to undergo Knee Joint Replacement Surgery.

Stem Cell therapy for knees, is a minimally invasive procedure that can result in phenomenal decrease in pain and inflammation, check further arthritic damage, restore the joint cartilage and cause delay or render surgery superfluous.

The Knee-Worthy Stem Cell Cartilage Regeneration Procedure

The primary purpose of the joint cartilage at the knee is to allow for smooth gliding of the joint surfaces and protect the surrounding bone from further damage. The Articular Cartilage has the potential to act as a shock absorber and hold up to 20 times the body weight. However, with the onset of osteoarthritis, either caused due to age or previous trauma there is gradual degeneration of this joint cartilage. This leads to acute pain due to friction and subsequently damages to the bone beneath the cartilage and the associated ligaments, tendons and muscles causing restriction in mobility.

A Note on the Stem Cells Extracted?

Adult Stem Cells have been tested to have the potential to multiply into cartilage, bone, fat or soft tissue. It has been found in this context that the injection of progenitor cells, especially the Mesenchymal Stem Cell restore degenerative cartilage far better than differentiated cells. They respond best to areas of inflammation and degeneration and cause modification to the immune system to contribute to the surrounding cartilage in affected areas.

knee cartilage regeneration chennai

How Stem Cell Treatment is Initiated

Stem Cells are present in abundance in the umbilical cord and small children. In adults they are localised in the hip and chest bones from where they are extracted using BMAC, a minimally invasive procedure. The same is then isolated using a special machine and the subsequently isolated stem cells are introduced in the damaged area through injection of two kinds:

1. PRP – Platelet rich Plasma
2. BMAC – Bone Marrow aspirate concentrate

The therapeutic use of these particular Stem Cells has been found to be perfectly safe and effective in the treatment of knee cartilage pain and osteoarthritis. Many patients have outlasted the need for any surgical intervention as a result of advanced Stem Cell therapy.

Knee cartilage Regeneration in Chennai

Contact TOSH (Trauma and Orthopaedic Speciality Hospital at Chennai) to find out more about this innovative treatment and gain the welcome support of the renowned orthopaedic specialists in Chennai
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Monday, 26 February 2018

Live Straight With Scoliosis Correction Surgery

What is Scoliosis?

Scoliosis is an abnormal curvature of the spine. The spinal curve may develop as a single curve (like C) or two curves (like S). Scoliosis condition does not give any significant symptoms in teens and children until the condition has progressed. Idiopathic and degenerative scoliosis are the most common types. There are three orthopedic options for treating scoliosis are observation, bracing or surgical intervention. When the first two options fail to improve the condition, Scoliosis Correction Surgery will be the last option.

Scoliosis Correction Surgery   

Spinal fusion is a surgical procedure in which the curved vertebrae are fused together. Then, the fused bones start to heal into a single and solid bone. This surgical method stops the growth in the abnormal spine segment and prevents the curve from getting worse. The spinal fusion is primarily used to reduce pain due to the abnormal vertebrae movement. Pain is diminished by stopping the movement of faulty vertebrae. Spinal fusion helps to treat many spinal deformities and scoliosis in one among them.
In the spinal fusion, a bone graft is done to promote the fusion. Generally, small bone pieces are placed into the spaces between vertebrae which have to be fused. Then, the bone starts to grow together.
Until the surgery ends, metal rods are used to hold the spine in place. With the help of hook, screw or wire the rods are attached to the spine. Normally from 4-8 hours is taken for the spinal fusion surgery and depends on the curve size, the time duration extends.


The hospital stay for the patient after the spinal fusion may be for 2-4 days. After the surgery, in the first few weeks, the patient is suggested with some basic exercises such as normal walking with a protective brace and few stretching exercises. Recovery may take from weeks to months depends on the patient condition.
TOSH (Trauma and Orthopedic Specialty Hospital) is one of the best orthopedic hospital in Chennai. The world-class treatment is offered by the expert and the best orthopedic specialists and it provides the best spinal surgery Chennai.

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Friday, 9 June 2017

Make Your Movements Perfect

Joint replacement surgery is a very effective way of reducing joint pain, improving a deformity, and supporting to improve patient’s mobility (movement). Generally, surgery is not consider as a last line of treatment but when other treatment such as medications and physical therapy have not helped then surgery is the only way to reduce the pain. People who are referred for joint replacement surgery often have
  • Severe joint pain
  • Limping
  • Stiffness
  • Muscle weakness
  • Swelling
  • Limited motion


People may have problem with daily activities such as walking, standing, getting into and out of cars, putting on socks and shoes, and climbing stairs depending on the level of affected joint and the damage level. The most common causes of not working of joints are rheumatoid arthritis and osteoarthritis. There are several factors that contribute in joint weakening and arthritis. They are
  • Heredity
  • Problem in joint development
  • Problem with cartilage
  • Minor repetitive injuries
  • Severe trauma to the joint cartilage
  • Overweight causes early joint problems

The three most common joint replacement surgeries are 

Joint replacement surgery is replaced the damaged cartilage and any other bone loss. The damaged joint is resurfaced and the patient’s ligaments and muscles are used for support and help during the surgery process. 
TOSH (Trauma and Orthopedic specially Hospital), Chennai has world class facilities for joint replacement surgery. TOSH is the prominent name for the knee, hip and shoulder surgery in the Chennai. The doctors of TOSH are well qualified and well known joint specialist in the Chennai. The environment of the hospital is patient centric and friendly. 


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Friday, 21 April 2017

Stem Cell Therapy : Alternative Treatment For Knee Replacement

Stem cell therapy has been in news for quite some time, for its magical regenerative properties. This has been put to use in treating several disorders effectively. Stem cell treatment for knee cartilage regeneration is one of the latest in the field, enabling a cure for knee arthritis without having to replace the joint.

Stem cells are special cells found in our body that could change or differentiate into other cells. They help in repairing or healing injuries by regenerating the harmed cells. However, when the injury or damage is bigger, an inability to recruit enough stem cells occurs. These can be rectified by extracting stem cells from other areas and concentrating their action in the site of injury. This is what stem cell procedures do.

Procedure for Knee Cartilage Regeneration Using Stem Cell

The stem cell treatment for knee cartilage regeneration involves a minimally invasive procedure. It is a latest development in the field of knee arthritis treatment. Here an arthroscopic procedure is done in the knee area to scrap off the portion of cartilage that is worn out due to arthritis. 

Stem cells are extracted from the bone marrow, that is aspirated from the patient’s hip bone and concentrated to cultivate stem cells and associated growth factors. This is then mixed with a clotting gel and injected into the knee joint area where the worn-out cartilage was scrapped out from. 

The stem cell treatment procedure is emerging as an alternative for total knee replacement surgery that is widely practised today. The ability of the procedure to retain one’s own knee has increased its popularity among patients.

Benefits of Stem Cell Treatment 

The main benefits of the treatment procedure are as below: -
  • Preserves our natural knee joint
  • Avoids the discomfort due to metal implants
  • No more restrictions in joint movements
  • Can continue with all daily activities with ease.
  • Very short recovery period
  • Can fully move the joint in a day
  • No prolonged hospitalisation required.

TOSH Trauma and Orthopaedic Specialty Hospital, Chennai, offers advanced orthopaedic treatments on par with the best in the world.

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Friday, 3 February 2017

Want Freedom from Your Back Pain ?

Herniated disc is a common medical situation among adults. In some people, herniated discs presses against the spinal cord or the nerve roots causing acute pain that is very difficult to bear. These cannot be completely treated with medication. Surgical processes are the best methods to deal with such cases. Discectomy is the surgical process that is done to remove herniated discs that presses against the spinal cord or the nerve roots.

An ortho specialist might suggest a discectomy when the patient has an acute pain on the leg or expresses weakness in the legs or complaint about numbness in the feet. Usually, the ortho specialist would wait for around a month to see if nonsurgical methods can improve the condition of the patient. The surgeon usually resorts to surgical methods only after he finds that medications have been ineffective. Loss of bowel or bladder control and possibility of losing motion of the limbs are also reasons that might force the doctor to go for a 
The doctor makes a small incision near the herniated part. He may remove a lamina of the infected part of the vertebrae to have a clearer vision of the herniated disc. Surgeon then cut off the herniated part of the disc. Any lose fragments of bone around the area might also be removed. The whole surgical process is usually done under general anaesthesia. Usually, the patient is made to walk on the first day after surgery. The patient would feel an instant vanishing of the pain but the numbness and weakness from the leg would subside only after few days.
Trauma and Orthopaedic Speciality Hospital (TOSH) is leading hospital that deals with all Joint Problems.  Dr. Zakeer Hussain at TOSH has been one of the prominent doctors in this field since long back. Utmost medical care is what discectomy require and that is exactly what one gets at TOSH.
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Wednesday, 25 January 2017

New Solution for Knee Pain

Stem Cell Therapies is advised if you have encountered an injury to the knee meniscus, cartilage, MCL or ACL ligaments, or have chronic knee pain due to a past injury or arthritis

Stem Cell Therapies have been used in different medical conditions to restore the function and improve the quality of life. In most of the cases, stem cell therapies have been lifesaving. Bone marrow transplant is the most widely used stem-cell therapy.

Stem cell therapy promotes the reparative response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. It is the advanced level of organ transplantation and makes uses of cells instead of donor organs, which are limited in supply.
Researchers culture stem cells in a laboratory. These stem cells are worked upon to specialize into specific types of cells, such as heart muscle cells, blood cells, bone marrow cells or nerve cells. The specialized cells can then be implanted into a person.
  • Speed up the length of time it takes for injuries or wounds to heal
  • Decrease nerve damage
  • Reduce pain, even chronic joint pain, with less need for medications
  • Increase functionality, range of motion, flexibility and sleep quality
  • Reduce muscle compensations and risk for future injuries
  • Return patients to their normal activities as quickly as possible

As with most of the medical procedure, stem cell therapy does come with minimal risks. However, advances in stem cell treatment have nullified many of the risks. The biggest risk is most patients undergoing stem cell therapy face is an infection from the extraction of adipose tissue or the injection of stem cells.
The recovery time from a stem cell therapy treatment is virtually none.  A stem cell therapy treatment is an outpatient procedure. Other than some minor discomfort at the injection site for a short time after the treatment, patients can return to work the next day. This makes stem cell therapy a great treatment alternative for all those who are concerned about the long recovery time associated with a surgical procedure.
TOSH Trauma & Orthopaedic Hospital is an exclusive orthopedic hospital with international standards. We offer a wide range of services in trauma and orthopedics, and also specialize in high-end primary and revision knee joint replacements.
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